Healthcare Professional
Intermediate
Featured
Diagnosis and Testing
A practical guide to diagnosing B12 deficiency in clinical practice. Learn to interpret serum B12 results in context, understand when to use functional markers like MMA and homocysteine, and apply current NICE and BSH guidance to real patient scenarios.
30 minutes4 sections1 CPD Points
Module Contents
This module consists of 4 sections
Introduction to B12 Testing
Video • 5 min
Preview Available
Interpreting Results
Interactive • 10 min
Diagnostic Algorithms
Content • 10 min
Assessment
Quiz • 5 min
Learning Objectives
By the end of this module, you will be able to:
- Apply NICE CKS and BSH diagnostic criteria
- Interpret serum B12 and related test results
- Identify when functional markers are needed
- Understand the limitations of B12 testing
- Develop a systematic diagnostic approach
Topics Covered
Serum B12: interpretation and limitations
MMA and homocysteine as functional markers
Holotranscobalamin (active B12)
Anti-intrinsic factor and anti-parietal cell antibodies
NICE and BSH diagnostic algorithms
When to treat empirically
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